Acute Liver Failure in Patients with Classic Heat Stroke

Authors

  • Jeremy J. Hernández-Ríos Faculty of Medicine, Autonomous University of Baja California, Mexicali, B.C., México. General Hospital of Mexicali, Mexicali, B.C., México
  • Fátima María Martínez-González Faculty of Medicine, Autonomous University of Baja California, Mexicali, B.C., México. General Hospital of Mexicali, Mexicali, B.C., México
  • Luz A. Gutiérrez-Bañales General Hospital of Mexicali, Mexicali, B.C., México
  • J. Andrés Beltrán-López Centre of University Studies of Xochicalco, Mexicali, B.C., México. General Hospital of Mexicali, Mexicali, B.C., México
  • Hiram J. Jaramillo-Ramírez General Hospital of Mexicali, Mexicali, B.C., México.

DOI:

https://doi.org/10.5195/ijms.2020.442

Keywords:

Heart stroke, Liver failure, Mortality

Abstract

Background: Classic heat stroke is defined by a core temperature greater than 40° C, severe dehydration and neurological alterations. Patients with liver disease due to heat stroke have been described, mostly by exercise. Hepatic failure is defined as the presence of a coagulopathy accompanied by any degree of hepatic encephalopathy. The primary objective of the study lies in the fact that patients who developed acute liver failure during their hospital stay had a higher risk of mortality.

Methods: A retrospective, analytical study of patients admitted to the General Hospital of Mexicali who suffered from classic heat stroke from March 2006 through August 2010, and a second period from June 2018 to August 2019.

Results: Fifty patients were recruited, the group included 48 (96%) male, with a total of 10 fatalities, representing 20%. INR greater than 1.5, AST and ALT levels were not related to an increased mortality rate.

Conclusion: Neither transaminase levels, nor liver failure, were related to a higher mortality rate in this cohort of patients with classic heat stroke.

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Author Biographies

Jeremy J. Hernández-Ríos, Faculty of Medicine, Autonomous University of Baja California, Mexicali, B.C., México. General Hospital of Mexicali, Mexicali, B.C., México

Medical Student (7th year)

Fátima María Martínez-González, Faculty of Medicine, Autonomous University of Baja California, Mexicali, B.C., México. General Hospital of Mexicali, Mexicali, B.C., México

Medical Student (7th year)

Luz A. Gutiérrez-Bañales, General Hospital of Mexicali, Mexicali, B.C., México

MD, General Practitioner.

J. Andrés Beltrán-López, Centre of University Studies of Xochicalco, Mexicali, B.C., México. General Hospital of Mexicali, Mexicali, B.C., México

Medical Student (6th year).

Hiram J. Jaramillo-Ramírez, General Hospital of Mexicali, Mexicali, B.C., México.

MD, Internal Medicine.

References

Giercksky T, Boberg KM, Farstad IN, Halvorsen S, Schrumpf E. Severe liver failure in exertional heat stroke. Scand J Gastroenterol. 1999 Aug; 34(8):824–7.

Leon LR, Bouchama A. Heat stroke. Compr Physiol. 2015 Apr; 5(2):611–47.

Figiel W, Morawski M, Grąt M, Kornasiewicz O, Niewiński G, Raszeja-Wyszomirska J, et al. Fulminant liver failure following a marathon: Five case reports and review of literature. World J Clin Cases. 2019 Jun; 7(12):1467–74.

Jaramillo-Ramírez HJ, Cota GL, Lomelí MR. Golpe de calor: un problema de salud pública en Mexicali. Salud Pública de México. 2011 Jul; 53(4):285–6. Spanish.

Busto Bea V, García-Alonso FJ, Moreira Vicente V. Afectación hepática en el golpe de calor. Med Clin (Barc). 2012 Apr; 138(8):361–5. Spanish.

Davis BC, Tillman H, Chung RT, Stravitz RT, Reddy R, Fontana RJ, et al. Heat stroke leading to acute liver injury & failure: A case series from the Acute Liver Failure Study Group. Liver Int. 2017 Apr; 37(4):509–13.

Munoz Santiago J, Stravitz RT, Don A. Gabriel. Coagulopathy of Acute Liver Failure. Clin Liver Dis 133. 2009 Feb;95-107.

Bernal William, Wendon Julia,. Acute Liver Failure. N Engl J Med. 2013 Mar; 369: 2525-34.

Butterworth Roger F. Pathogenesis of Hepatic Encephalopathy and Brain Edema in Acute Liver Failure. J Clin Exp Hepatol. 2014 Mar; 1-8.

Jin Q, Chen E, Jiang J, Lu Y. Acute Hepatic Failure as a Leading Manifestation in Exertional Heat Stroke. Case Rep Crit Care. 2012 Jun; 2012:1-4.

Trujillo MH, Fragachán G. C. Rhabdomyolysis and Acute Kidney Injury due to Severe Heat Stroke. Case Reports in Critical Care. 2011 Sep; 2011:1–4.

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Published

2020-08-31

How to Cite

Hernández-Ríos, J. J., Martínez-González, F. M., Gutiérrez-Bañales, L. A., Beltrán-López, J. A., & Jaramillo-Ramírez, H. J. (2020). Acute Liver Failure in Patients with Classic Heat Stroke. International Journal of Medical Students, 8(2), 111–113. https://doi.org/10.5195/ijms.2020.442

Issue

Vol. 8 No. 2 (2020)

Section

Short Communication

Categories

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